(+/-) RK-682 Citation Available Product Size(s) 200 ug £135.00 10-4300-200UG Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: 10-4300-200UG Extra Details: RK-682 is a protein tyrosine phosphatase inhibitor (IC50's = 54 uM for CD45, 2.0 uM for VHR; did not inhibit cdc25B) originally isolated from the fermentation of Streptomyces sp. 88-682.1 Inhibits cell cycle at G1/S. RK-682 has also been shown to inhibit PLA2 (IC50 = 16 uM)2, HIV-1 protease (IC50 = 84 uM)3, and heparanase (IC50 = 17 uM)4. Natural RK-682 (R-isomer) and synthetic racemic material have identical phosphatase activity.5 Care should be taken when using RK-682 in the presence of metal salts - RK-682 readily forms metal complexes that affects its phosphatase inhibitory activity.6 RK-682 has been identified as a potential promiscuous inhibitor.7 Molecular Weight: 368.52 Purity: 98% Shipping Conditions: Ambient Storage Conditions: -20[o]C Supplier: Focus Biomolecules Size: 200 ug Manufacturer's Data Sheet: Need Help? View product citations for proteins 10-4300-200UG on CiteAb