Focus Biomolecules

Focus Biomolecules was founded by former members of globally recognised BIOMOL. From their industry experience they set out to refine the practices of small molecule based life sciences companies and eliminate the challenges too often found by customers. With more than 24 years in the industry, they offer advanced, high quality reagents and a fresh, customer oriented experience.

View All Focus Biomolecules Products

Essential Biochemicals for Bioprocessing

Focus Biomolecules offer a broad portfolio of cutting-edge biochemicals with specific utility in bio-processing. Their bioprocessing agents will allow you control cell selection, growth, and function which will maximize protein expression, yield, glycosylation, integrity and minimize degredation, both upstream and downstream. Key product groups include:

Antibiotics & Antifungals	Cell cycle modulators	Ionophores
Cofactors & Coenzymes	Glycosylation inhibitors	Selection & Amplification reagents
Apoptosis & Autophagy Modulators	Protease inhibitors	Differentiation agents
Cell growth modulators	Protein expression modulators	Stem Cell Effectors

These products can be used to establish conditions during early stage assessment and upstream process development, to ensure optimization at every step. These include chemically defined medium design, feed/supplement selection, expression host selection, lead candidate production, process optimization, scaleup and validation.

Below is just a selection of our bioprocessing chemicals. You won't see these listed with other bioprocessing suppliers, because these are on the cutting-edge for controlling protein titer, post-translational modification, and other critical parameters. Ask us for our full product listing, which includes our comprehensive offering of bioprocessing products along with literature references and other useful information.

Product Name	Mechanism	Bioprocessing Effect	Category
Rosmarinic acid	Antioxidant (ROS scavenger)	Increases recombinant protein production: Reduces glycation and formation of acidic charge variants	Protein production/ titre
Bafilomycin A1	Autophagy inhibitor (Vacuolar H+ -ATPase inhibitor)	Increases recombinant protein expression in cells	Protein production/ titre
Prostaglandin E2	Promotes proliferation (EP4 receptor activator)	Increases cell specific productivity	Protein production/ titre
Aphidicolin	Cell cycle arrest (DNA polymerase inhibitor)	Enhances transfection efficiency	Protein production/ titre
Coenzyme A	Cofactor (Essential)	Essential for many metabolism pathways	Cell growth and function
7-alpha Hydroxy-c\ holesterol	Building block (Essential)	Improved cell function results in higher protein expression levels in some cell cycles	Cell growth and function
Mycophenolicacid	Fucosylation modulator	Retention of essential post-translational modification on therapeutic protein	Therapeutic protein integrity
Trichostatin A	HDAC inhibitor (Reduces epi- genetic transcriptional repression)	Increases recombinant protein expression	Protein production/ titre
Brefeldin A	Intracellular transport inhibitor	Modulates protein titre and integrity	Scaleup and analysis
Chloroquine phosphate	Improves transfection; increases cell specific productivity; fine tunes glycosylation	Modulates protein titre and integrity	Scaleup and analysis

Cancer Cell Metabolism Products

Focus offers a wide range of modulators of cancer cell metabolism pathways.

Find Out More!

STING

The cGAS-STING pathway is A SUPER HOT AREA OF RESEARCH right now. At the last Inflammation Research Association meeting there was an entire session on this topic. Many papers on the topic are being published, pharma companies have started programs in this area and even new drug discovery companies are being formed based on this platform.

Further information!