VivopureX[TM] Recombinant Antibodies for In Vivo Research

Engineered mouse antibodies available at bulk discounts!

VivopureX™ antibodies are recombinant mouse antibodies ideal for in vivo research in mouse models. The collection consists of popular antibody clones, many originally obtained from rats or hamsters, which Absolute Antibody has engineered into mouse-anti mouse recombinant versions to improve research results.

VivopureX™ recombinant antibodies offer many advantages compared to the original monoclonal antibodies, including increased long-term efficacy, stronger potency and a more consistent response across cohorts. They also feature engineered effector functions, with Fc receptor binding tailored to best suit popular applications such as depletion, agonism or blocking.

The VivopureX™ Antibody Collection

The VivopureX™ collection includes a selection of our most exciting mouse-anti-mouse antibodies, now available at competitively priced bulk prices. All are available in discounted bulk sizes ranging from 1 mg to 100 mg, as well as our standard 200 μg size.

Antibody Name [Clone]	Engineered Format	Available Bulk Sizes
Anti-OX40/CD134 [OX86]	Mouse IgG1 or IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-PD-1[RMP1-14]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CTLA-4 [9D9]	Mouse IgG2a or Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-GITR [DTA-1]	Mouse IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD25 [PC-61.5.3]	Mouse IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-TIGIT [1B4]	Mouse IgG1	1 mg, 10 mg, 25 mg, 100 mg
Anti-Lag3 [C9B7W]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD96 [6A6]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-IL-10R [1B1.3a]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-B7-H4 [7A1-6]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-BTLA [HMBT-6B2]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-Tim-4 [3A1]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-Tim-4 [5G3]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-TIM-2 [RMT2-14]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-Tim-1 [3B3]	Mouse IgG1	1 mg, 10 mg, 25 mg, 100 mg
Anti-Tim-3 [2C12]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD115/M-CSFR [AFS98]	Mouse IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-PD-L1 [10F.9G2]	Mouse IgG2b or Mouse IgG2b Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-IFN-gamma receptor 1 {GR20]	Mouse IgG2b Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-VISTA [13F3]	Mouse IgG2b Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD20 [18B12]	Mouse IgG2a	10 mg, 25 mg, 100 mg
Anti-CD4 epitope A [YTS 177.9]	Mouse IgG2a	10 mg, 25 mg, 100 mg
Anti-CD4 epitope A [YTS 191.1]	Mouse IgG2a	10 mg, 25 mg, 100 mg
Anti-CD8 alpha/Lyt-2 [YTS 169.4]	Mouse IgG2a	10 mg, 25 mg, 100 mg
Anti-Ly6G [1A8]	Mouse IgG2a	10 mg, 25 mg, 100 mg
Anti-CD200R [OX131]	Mouse IgG1 Fc Silent™	10 mg, 25 mg, 100 mg
Anti-PD-L2 [TY25]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-Ly6G/Ly6C [RB6-8C5]	Mouse IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-Galectin 9 [RG9-35]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD153 [RM153]	Mouse IgG2a or Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD155 [3F1]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD226 [10E5]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD47 [mIAP301]	Mouse IgG2b Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD45R [RA3-6B2]	Mouse IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD19 [6D5]	Mouse IgG2a	1 mg, 10 mg, 25 mg, 100 mg
Anti-HVEM [HMHV-1B18]	Mouse IgG2a Fc Silent™	1 mg, 10 mg, 25 mg, 100 mg
Anti-CD27 [RM27-3E5]	Mouse IgG1	1 mg, 10 mg, 25 mg, 100 mg

Benefits of Species-Matched Antibodies

Our VivopureX™ antibodies offer many advantages compared to the original antibody format, as illustrated by our data below. In this example, our recombinant mouse PD-1 antibody based on the widely used clone RMP1-14 reduced tumor size in a mouse model more effectively than the original rat version.

Reduced immunogenicity: no neutralizing antibodies are induced in the host organism, meaning the antibody works for longer and cohorts respond more consistently
Tailored effector function: the antibody format has been engineered to suit its most popular applications
Increased potency: less antibody is required to achieve the same response in mouse models
Batch-to-batch reproducibility: recombinant production ensures the highest possible reproducibility, while guaranteeing high purity and low endotoxin levels

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VivopureX[TM] Recombinant Antibodies for In Vivo Research

The VivopureX™ Antibody Collection

Benefits of Species-Matched Antibodies

A graph to show the use of VivopureX on tumour volume.

Basket

VivopureX[TM] Recombinant Antibodies for In Vivo Research

The VivopureX™ Antibody Collection

Benefits of Species-Matched Antibodies

A graph to show the use of VivopureX on tumour volume.

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