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Bio X Cell InVivoSIM™ non-therapeutic antibodies are research-grade biosimilar monoclonal antibodies that have the same active biological component as the original therapeutic antibodies. Biosimilars make it possible to study the biological effects of a drug without the need to source an expensive pharmaceutical-grade therapeutic.
Our InVivoSIM™ antibodies feature greater than 95% purity and are free of preservatives, stabilizers, and carrier proteins. InVivoSIM™ antibodies are screened for murine pathogens and protein aggregation, feature binding validation via Immunoblot and are guaranteed to contain less than 1 endotoxin unit per milligram. InVivoSIM™ antibodies are for Research Use Only (RUO) and are not for therapeutic use.
| InVivoSIM™ SKU |
Product Name |
Application |
| SIM0010 |
InVivoSIM anti-human PD-1 (Pembrolizumab Biosimilar) |
Blocking of PD-1/PD-L signaling;
Functional Assay |
| SIM0005 |
InVivoSIM™ anti-human HER2 (Trastuzumab Biosimilar) |
FC; ELISA; IHC; WB |
| SIM0009 |
InVivoSIM™ anti-human PD-L1 (Atezolizumab Biosimilar) |
FC; WB |
| SIM0002 |
InVivoSIM™ anti-human EGFR (Cetuximab Biosimilar) |
GFR blockade; ELISA; FC |
| SIM0008 |
InVivoSIM™ anti-human CD20 (Rituximab Biosimilar) |
FC; ELISA; WB |
| SIM0007 |
InVivoSIM™ anti-human VEGF (Bevacizumab Biosimilar) |
VEGF neutralization; FC; ELISA; IP |
| SIM0001 |
InVivoSIM™ anti-human TNFα (Adalimumab Biosimilar) |
TNFα neutralization; FC, ELISA; IF; IP; IHC; WB |
| SIM0003 |
InVivoSIM™ anti-human PD-1 (Nivolumab Biosimilar) |
Blocking of PD-1/PD-L signaling; FC; IHC; WB |
| SIM0004 |
InVivoSIM™ anti-human CTLA-4 (Ipilimumab Biosimilar) |
CTLA-4 neutralization; FC; ELISA; WB |
| SIM0006 |
InVivoSIM™ anti-human TNFα (Infliximab Biosimilar) |
TNFα neutralization; FC; ELISA; WB |
| SIM0014 |
InVivoSIM anti-human IL-6R (Tocilizumab Biosimilar) |
Functional Assays; ELISA |
| SIM0012 |
InVivoSIM anti-human VEGFR-2 (Ramucirumab Biosimilar) |
Functional Assays; ELISA; IHC |
| SIM0011 |
InVivoSIM anti-human C5 (Eculizumab Biosimilar) |
C5-Inhibition; Functional Assays; ELISA; IP |
| SIM0013 |
InVivoSIM anti-human IL-17A (Secukinumab Biosimilar) |
Functional Assays; ELISA; IF; IHC; FC |
IF Immunofluorescence | IHC-F Immunohistochemistry (frozen) | IHC-P Immunohistochemistry (parrafin) | WB Western blot | IP Immunoprecipitation | FC Flow cytometry (requires flurochrome conjugation)